Introduction to Epidemiology

This material serves as brief overview and an introduction to the uses, methodology and clinical application of epidemiology. The main goals are to:

  • State the main applications and uses of epidemiology
  • Identify the most commonly used study designs
  • Understand the advantages and limitations of epidemiological measurements
  • Apply the knowledge gained by critically evaluating the medical literature
  • Define evidence-based medicine
  • Create a clinical query based on a patient’s chief complaint
  • Apply the knowledge gained by effectively searching medical databases to answer clinical queries.

Course Outline

Epidemiology

Introduction:

  • History of Epidemiology
  • Concepts in Infectious Disease Epidemiology
  • Introduction to Biostatistical Concepts

Study Designs I:

  • Randomized Controlled Trials
  • Cohort Studies

Study Designs II:

  • Case-Control Studies
  • Ecologic Studies
  • Cross-Sectional Studies

Threats to Validity:

  • Confounding and Bias

Interaction:

  • Approaches in SAS

Evidence-Based Medicine

Introduction:

  • Definitions
  • Elements of EBM
  • PICO, Sources and Searches

Diagnosis:

  • Sensitivity, Specificity,
  • Positive and Negative Predictive Values
  • Likelihood Ratios, SNout, SPin

Treatment:

  • Number Needed to Treat / Harm